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Schizophrenia is a severe mental disorder characterized by a range of symptoms from hallucinations to social withdrawal. It involves genetic predispositions and environmental triggers, with neurobiological research highlighting neurotransmitter dysfunctions. Structural brain abnormalities and altered brain activation patterns are also evident. The diathesis-stress model integrates these biological, psychological, and social factors, offering a comprehensive understanding of schizophrenia's etiology.
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Positive symptoms of schizophrenia include hallucinations and delusions
Social Withdrawal
Negative symptoms of schizophrenia can manifest as social withdrawal and diminished emotional expression
Diminished Emotional Expression
Negative symptoms of schizophrenia can manifest as social withdrawal and diminished emotional expression
Schizophrenia can have a profound impact on individuals, leading to challenges in daily functioning and social integration
Schizophrenia has a strong genetic basis, with an estimated heritability of 80%
The development of schizophrenia is also influenced by environmental triggers
Schizophrenia is a polygenic disorder, with multiple genes contributing small effects
Neurobiological research has implicated dysfunctions in neurotransmitter systems, particularly dopamine, glutamate, and serotonin, in the pathophysiology of schizophrenia
Neuroimaging studies have consistently found structural brain abnormalities in individuals with schizophrenia
Structural changes in the brain are associated with functional impairments in cognition, memory, and executive functions
Stressful life events can interact with biological vulnerabilities to trigger the onset of schizophrenia
The expressed emotion hypothesis suggests that high levels of criticism and emotional over-involvement in families can increase the risk of relapse in schizophrenia
Social factors, such as poverty, urbanicity, and migration, have been associated with a higher incidence of schizophrenia
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The origins of ______ are complex, involving both genetic factors and ______ influences.
schizophrenia
environmental
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Schizophrenia heritability estimate
Approximately 80%, indicating strong genetic influence.
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Nature of genetic contribution in schizophrenia
Polygenic, with multiple genes each contributing small effects.
