Cosmid vectors are crucial in genetic engineering for cloning large DNA fragments, often between 35 to 45 kilobase pairs. They combine plasmid and bacteriophage lambda DNA, enabling the construction of genomic libraries and the advancement of gene therapy. Despite challenges in handling, cosmids are key to studying gene function and creating genetically modified organisms.
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1
In genetic engineering, cosmids are used for gene therapy and creating ______, important for genome analysis.
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2
Cosmid vector role in cloning
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3
Transfection in cosmid cloning
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4
Lambda phage particles in cosmids
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5
The ______ Project benefited from cosmid libraries for DNA sequencing and analysis.
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6
Cosmid vectors vs. standard plasmids for large DNA fragments
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7
Cosmid vectors' DNA size requirement for packaging
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8
Comparison of cosmids with BACs and YACs in library construction
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9
Cosmid vectors are created by first ______ a plasmid vector and then inserting a DNA fragment.
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10
Cosmid vectors: cloning capacity
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11
Cosmid vectors: applications
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12
Cosmid vectors: challenges
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