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Pacinian corpuscles are mechanoreceptors in the skin that detect vibrations and deep pressure. Located in fingertips, joints, and more, they play a key role in touch and proprioception. Their structure, with concentric lamellae, allows them to transduce mechanical stimuli into electrical signals, enabling our nervous system to process sensations of touch and movement.
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Pacinian corpuscles consist of a central nerve ending surrounded by concentric layers of connective tissue that act as a mechanical filter
Pacinian corpuscles are particularly sensitive to rapid pressure changes and can generate a nerve impulse if strong enough
Pacinian corpuscles convert mechanical pressure into an electrical signal through the opening of ion channels in the neuron's membrane
Pacinian corpuscles are sensory receptors that play a crucial role in converting various forms of stimuli into electrical signals for the nervous system to interpret
Pacinian corpuscles are strategically located in areas of the body that require sensitivity to vibration and pressure, such as the fingertips, soles of the feet, and erogenous zones
Pacinian corpuscles also contribute to proprioception, the body's ability to sense its position and movement in space, by being located in deeper tissues like joints, pancreas, and around muscles
When pressure is applied, Pacinian corpuscles convert it into an electrical signal through the opening of ion channels in the neuron's membrane
After firing an action potential, Pacinian corpuscles enter a refractory period to prevent overlapping signals and accurately convey sensory information to the nervous system
The influx of sodium ions into the cell during sensory transduction is responsible for depolarization and the initiation of a neural signal
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Location of Pacinian corpuscles
Located in deep layers of skin; detect deep pressure and rapid vibrations.
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Structure of Pacinian corpuscles
Onion-like; central nerve ending surrounded by concentric connective tissue layers.
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Function of concentric layers in Pacinian corpuscles
Act as mechanical filter; deform with rapid pressure changes to generate potential.
