The Viral Lytic Cycle is a fundamental process by which virulent viruses replicate and destroy host cells, encompassing Attachment, Penetration, Biosynthesis, Maturation, and Release. Understanding this cycle is crucial for developing antiviral strategies and has applications in gene therapy and genetic engineering. Bacteriophage T4 demonstrates the cycle's efficiency and its impact on viral propagation.
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The initial interaction between a virus and a host cell, determining the host range
Biosynthesis
The stage where viral DNA or RNA and proteins are produced using the host's cellular machinery
The process of a virus entering a host cell and releasing its genetic material
The stage where new virions are put together within the host cell
The final stage where progeny viruses exit the host cell, often causing cell lysis and spreading to infect new cells
The Lytic Cycle is essential for the spread of viral diseases, particularly those causing acute infections with rapid onset and severe symptoms
The efficiency of the Lytic Cycle is often a reflection of a virus's ability to cause disease
The mechanisms of the Lytic Cycle are utilized in gene transfer and gene therapy, offering potential solutions for genetic diseases and advancements in agricultural biotechnology
Both cycles involve Attachment and Entry, but diverge in subsequent stages
In the Lysogenic Cycle, the viral genome can remain dormant and may be induced to enter the Lytic Cycle under specific triggers
The ability of viruses to switch between cycles allows them to establish latent or chronic infections, posing challenges for diagnosis and treatment
A model for the Lytic Cycle, infecting E. coli bacteria and illustrating the stages of the cycle
00
In the ______ phase of the Viral Lytic Cycle, the virus attaches to the host cell receptors, influencing the range of possible hosts.
Attachment
01
During the ______ stage of the Viral Lytic Cycle, new viral DNA or RNA and proteins are synthesized using the host cell's resources.
Biosynthesis
02
Initial stage of Viral Lytic Cycle
Attachment - virus binds to host cell surface.
