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Explore the regulation of inducible genes, transcriptional control, and post-transcriptional mechanisms that influence gene expression. Learn how environmental stimuli and regulatory signals within cells can increase or decrease gene expression levels. Understand the roles of transcription factors, enhancers, DNA methylation, and non-coding RNAs in gene transcription, and their impact on processes like neuroplasticity and oncogenesis.
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Inducible genes are genes whose expression levels can be altered in response to specific environmental stimuli or regulatory signals
Transcription
Gene expression involves the transcription of DNA into mRNA, which is then translated into proteins
Translation
mRNA is translated into proteins, which can be regulated to control gene expression
Transcription Factors
Transcription factors bind to DNA and can activate or repress gene expression
Histone Modification
The modification of histones can affect chromatin structure and gene expression
Non-coding RNAs
Non-coding RNAs can modulate gene activity and regulate gene expression
Transcriptional regulation involves genetic, epigenetic, and post-translational mechanisms that control gene expression
Transcription factors can activate or repress transcription by binding to specific DNA sequences and undergoing post-translational modifications
The nuclear membrane regulates the access of transcription factors to DNA, adding a spatial dimension to transcriptional control
Enhancers are DNA sequences that can increase the transcription of genes even when located far from the gene's promoter
Enhancers function by physically interacting with promoters through DNA looping, facilitated by architectural proteins
Enhancers are activated by transcription factors and coactivator complexes, leading to increased transcription of target genes
DNA methylation is an epigenetic modification that can affect gene expression by adding a methyl group to cytosine bases
Methylation in gene promoters can lead to transcriptional repression, while methylation within genes can be associated with active transcription
DNA methylation is dynamically regulated by DNA methyltransferases and TET enzymes, which add or remove methyl groups
00
Gene expression regulation can involve ______ factors, histone modifications, and non-coding RNAs.
transcription
01
The production of ______ is regulated in accordance with blood glucose levels.
insulin
02
Role of transcription factors in gene regulation
Transcription factors bind to DNA sequences like enhancers, silencers, promoters; activate or repress transcription.
